Successful treatment of Miescher's cheilitis in Melkersson-Rosenthal syndrome with betamethasone injections and doxycycline

Clofazimine--an effective treatment for Melkersson-Rosenthal syndrome or Miescher's cheilitis.

Melkersson-Rosenthal syndrome (MR) is a rare condition which was initially described in 1928 hy Melkersson who detected a relationship between facial palsy and swelling of the face. The triad is completed by lingua plicata which was described by Rosenthal in 1931. Cases have been reported and the condition reviewed by Graff-Radford, (1981); Azaz and Nitzan, (1984); Wadlington, Riley and Lowbeer...

Melkersson-Rosenthal syndrome: Appropriate response to the combination treatment with intralesional triamcinolone injection and oral azithromycin

Melkersson-Rosenthal syndrome is an uncommon disorder which is presented by a triad of lip swelling, facial nerve palsy, and a fissured tongue. A number of treatments have been reported for this syndrome with variable outcomes. We have reported a 38-year-old female patient with lower lip swelling and a fissured tongue on clinical examination. She was also suffering from facial nerve paralysis s...

Surgical treatment of persistent macrocheilia in patients with Melkersson-Rosenthal syndrome and cheilitis granulomatosa.

BACKGROUND Various conservative methods for treatment of labial swelling in patients with cheilitis granulomatosa have been attempted, often with only moderate success and sometimes with persistent disfiguring lip swelling. Severe macrocheilia can produce an unaesthetic facial deformity associated with functional disturbances. In patients with persistent macrocheilia, reduction cheiloplasty wit...

Orofacial granulomatosis treated with intralesional triamcinolone.

Orofacial granulomatosis (OFG) is an uncommon disease, usually presenting as recurrent or persistent swelling of the soft tissues in the orofacial region, predominantly lips (cheilitis granulomatosa). The cause of this illness is unknown. OFG may also be part of the triad of Melkersson-Rosenthal syndrome (MRS) and some consider it a monosymptomatic form of MRS. We describe a case of a Croatian ...

Cheilitis granulomatosa associated with melkersson - rosenthal syndrome Summary